FURIN antibody (N-Term)

Catalog No. ABIN2782180

Product Details anti-FURIN Antibody

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Sheep, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FURIN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RDVYQEPTDP KFPQQWYLSG VTQRDLNVKA AWAQGYTGHG IVVSILDDGI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FURIN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FURIN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 794 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FURIN

Target: FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))

Alternative Name: FURIN (FURIN Products)

Background: The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a c
Alias Symbols: FUR, PACE, PCSK3, SPC1
Protein Interaction Partner: env, UBC, ABCC6, ELAVL1, ZP4, ITM2C, COL23A1, NAGPA, SORCS1, BACE1, PACS1, ADAMTS1, LECT1, TNFSF13, ADAMTS4, ADAM19, SORL1, SERPINB8, AP2M1, EDA, FLNA, VWF, NOTCH1, ZP3, PRB4, PMCH, PDGFA, DSG3, FURIN, LRP1, FLNC,
Protein Size: 794

Molecular Weight: 74 kDa

Gene ID: 5045

NCBI Accession: NM_002569, NP_002560

UniProt: P09958

Pathways: Notch Signaling, Neurotrophin Signaling Pathway