ITGB8 antibody (C-Term)

Catalog No. ABIN2782163

Product Details anti-ITGB8 Antibody

Target: ITGB8 (Integrin beta-8 (ITGB8))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: CTDPRSIGRF CEHCPTCYTA CKENWNCMQC LHPHNLSQAI LDQCKTSCAL

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ITGB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ITGB8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 769 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ITGB8

Target: ITGB8 (Integrin beta-8 (ITGB8))

Alternative Name: ITGB8 (ITGB8 Products)

Synonyms: 4832412O06Rik antibody, integrin beta 8 antibody, integrin subunit beta 8 antibody, Itgb8 antibody, ITGB8 antibody

Background: ITGB8 is a member of the integrin beta chain family and is a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation.This gene is a member of the integrin beta chain family and encodes a single-pass type I membrane protein with a VWFA domain and four cysteine-rich repeats. This protein noncovalently binds to an alpha subunit to form a heterodimeric integrin complex. In general, integrin complexes mediate cell-cell and cell-extracellular matrix interactions and this complex plays a role in human airway epithelial proliferation. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: -
Protein Interaction Partner: UBC, ITGAV, VTN, TGFB1,
Protein Size: 769

Molecular Weight: 81 kDa

Gene ID: 3696

NCBI Accession: NM_002214, NP_002205

UniProt: P26012