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ACP2 antibody (Middle Region)

ACP2 Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2782134
  • Target See all ACP2 Antibodies
    ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))
    Binding Specificity
    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 15
    • 3
    Rabbit
    Clonality
    • 15
    • 3
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ACP2 antibody is un-conjugated
    Application
    • 11
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    VPITEDRLLK FPLGPCPRYE QLQNETRQTP EYQNESSRNA QFLDMVANET
    Predicted Reactivity
    Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against ACP2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human ACP2
    Top Product
    Discover our top product ACP2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 423 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))
    Alternative Name
    ACP2 (ACP2 Products)
    Synonyms
    ACP2 antibody, Acp-2 antibody, LAP antibody, acid phosphatase 2, lysosomal antibody, acid phosphatase 2, lysosomal S homeolog antibody, ACP2 antibody, acp2 antibody, Acp2 antibody, acp2.S antibody
    Background
    ACP2 is the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.Lysosomal acid phosphatase is comprised of two subunits, alpha and beta, and is chemically and genetically distinct from red cell acid phosphatase. Lysosomal acid phosphatase 2 is a member of a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Acid phosphatase deficiency is caused by mutations in the ACP2 (beta subunit) and ACP3 (alpha subunit) genes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: FBXO6, NIF3L1, DNAJB11, UQCRFS1, M6PR, UBC,
    Protein Size: 423
    Molecular Weight
    45 kDa
    Gene ID
    53
    NCBI Accession
    NM_001610, NP_001601
    UniProt
    P11117
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