LFNG antibody (N-Term)
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- Target See all LFNG Antibodies
- LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Guinea Pig, Saccharomyces cerevisiae, Cow, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LFNG antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LSEYFSLLTR ARRDAGPPPG AAPRPADGHP RPLAEPLAPR DVFIAVKTTK
- Predicted Reactivity
- Cow: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%
- Characteristics
- This is a rabbit polyclonal antibody against LFNG. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human LFNG
- Top Product
- Discover our top product LFNG Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 361 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))
- Alternative Name
- LFNG (LFNG Products)
- Synonyms
- SCDO3 antibody, AW061165 antibody, id:ibd2614 antibody, id:ibd5029 antibody, id:ibd5138 antibody, l-fng antibody, wu:fc69h02 antibody, wu:fi34c01 antibody, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase antibody, LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase S homeolog antibody, LFNG antibody, Lfng antibody, lfng.S antibody, lfng antibody
- Background
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LFNG is a member of the glycosyltransferase superfamily. It is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in the gene that encodes this protein have been associated with autosomal recessive spondylocostal dysostosis 3. This gene encodes a member of the glycosyltransferase superfamily. The encoded protein is a single-pass type II Golgi membrane protein that functions as a fucose-specific glycosyltransferase, adding an N-acetylglucosamine to the fucose residue of a group of signaling receptors involved in regulating cell fate decisions during development. Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Alternatively spliced transcript variants that encode different isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: SCDO3
Protein Interaction Partner: APP, NOTCH2, NOTCH1,
Protein Size: 361 - Molecular Weight
- 39 kDa
- Gene ID
- 3955
- NCBI Accession
- NM_001040168, NP_001035258
- Pathways
- Notch Signaling
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