AREL1 antibody (N-Term)

Catalog No. ABIN2782048

Product Details anti-AREL1 Antibody

Target: AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1 (AREL1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AREL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LTCGQPHTLQ IVPRDEYDNP TNNSMSLRDE HNYTLSIHEL GPQEEESTGV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against KIAA0317. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KIAA0317

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 823 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-AREL1 antibody (ABIN2782048)

Lear, McKelvey, Rajbhandari, Dunn, Coon, Connelly, Zhao, Kass, Zhang, Liu, Chen: "Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4." in: The Journal of experimental medicine, Vol. 213, Issue 6, pp. 1029-46, (2016) (PubMed).

Target Details for AREL1

Target: AREL1 (Apoptosis Resistant E3 Ubiquitin Protein Ligase 1 (AREL1))

Alternative Name: KIAA0317 (AREL1 Products)

Synonyms: KIAA0317 antibody, apoptosis resistant E3 ubiquitin protein ligase 1 antibody, AREL1 antibody

Background: KIAA0317 contains 1 filamin repeat and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. The exact function of KIAA0317 remains unknown.
Alias Symbols: KIAA0317,
Protein Interaction Partner: UBC, Htra2, DIABLO, AREL1, UBE2D1, SEPT4, HSP90AA1,
Protein Size: 823

Molecular Weight: 94 kDa

Gene ID: 9870

NCBI Accession: NM_001039479, NP_001034568

UniProt: O15033