GALC antibody (Middle Region)
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- Target See all GALC Antibodies
- GALC (Galactosylceramidase (GALC))
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Binding Specificity
- Middle Region
- Reactivity
- Human, Rat, Mouse, Dog, Cow, Rabbit, Horse, Pig, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GALC antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LMTAQEPWSG HYVVESPVWV SAHTTQFTQP GWYYLKTVGH LEKGGSYVAL
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against GALC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human GALC
- Top Product
- Discover our top product GALC Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 685 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GALC (Galactosylceramidase (GALC))
- Alternative Name
- GALC (GALC Products)
- Synonyms
- 2310068B06Rik antibody, A930008M05Rik antibody, AW212969 antibody, AW413532 antibody, Gacy antibody, twi antibody, twitcher antibody, galc antibody, galcl antibody, zgc:92561 antibody, si:ch211-199l3.4 antibody, GALCERase antibody, wu:fi04e07 antibody, zgc:56444 antibody, galactosylceramidase antibody, galactosylceramidase a antibody, Galactosylceramidase antibody, galactosylceramidase L homeolog antibody, galactosylceramidase b antibody, GALC antibody, Galc antibody, galca antibody, galc antibody, Caci_7107 antibody, Bacsa_1415 antibody, Spico_0384 antibody, LOC100304802 antibody, galc.L antibody, galcb antibody
- Background
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GALC is a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy.This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: -
Protein Interaction Partner: TRAF3,
Protein Size: 685 - Molecular Weight
- 73 kDa
- Gene ID
- 2581
- NCBI Accession
- NM_000153, NP_000144
- UniProt
- P54803
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