CISD2 antibody (N-Term)

Catalog No. ABIN2781919

Product Details anti-CISD2 Antibody

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Rabbit, Zebrafish (Danio rerio), Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CISD2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VLESVARIVK VQLPAYLKRL PVPESITGFA RLTVSEWLRL LPFLGVLALL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Characteristics: This is a rabbit polyclonal antibody against CISD2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CISD2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 135 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CISD2

Target: CISD2 (CDGSH Iron Sulfur Domain 2 (CISD2))

Alternative Name: CISD2 (CISD2 Products)

Synonyms: ERIS antibody, Miner1 antibody, NAF-1 antibody, WFS2 antibody, ZCD2 antibody, 1500009M05Rik antibody, 1500026J14Rik antibody, 1500031D15Rik antibody, AI848398 antibody, B630006A20Rik antibody, Noxp70 antibody, Zcd2 antibody, RGD1566242 antibody, zgc:64148 antibody, eris antibody, miner1 antibody, wfs2 antibody, zcd2 antibody, cisd2 antibody, BcDNA:RE49709 antibody, Dmel\\CG1458 antibody, CDGSH iron sulfur domain 2 antibody, CDGSH iron sulfur domain 2 L homeolog antibody, CDGSH iron sulfur domain 2 S homeolog antibody, CISD2 antibody, Cisd2 antibody, cisd2 antibody, cisd2.L antibody, cisd2.S antibody

Background: CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum. It binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2 (WFS2).
Alias Symbols: ERIS, Miner1, WFS2, ZCD2, NAF-1
Protein Interaction Partner: UBC, LMNA, APP, SPP1, BCL2, ELAVL1,
Protein Size: 135

Molecular Weight: 15 kDa

Gene ID: 493856

NCBI Accession: NM_001008388, NP_001008389

UniProt: Q8N5K1

Pathways: Activation of Innate immune Response