Ectodysplasin A antibody (Middle Region)
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- Target See all Ectodysplasin A (EDA) Antibodies
- Ectodysplasin A (EDA)
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Goat, Guinea Pig, Horse, Dog, Rabbit
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Ectodysplasin A antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- HLQGQGSAIQ VKNDLSGGVL NDWSRITMNP KVFKLHPRSG ELEVLVDGTY
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against EDA. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human EDA
- Top Product
- Discover our top product EDA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 389 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." in: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).
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Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice." in: Developmental biology, Vol. 317, Issue 2, pp. 614-9, (2008) (PubMed).
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- Target
- Ectodysplasin A (EDA)
- Alternative Name
- EDA (EDA Products)
- Synonyms
- ECTD1 antibody, ED1 antibody, ED1-A1 antibody, ED1-A2 antibody, EDA-A1 antibody, EDA-A2 antibody, EDA1 antibody, EDA2 antibody, HED antibody, HED1 antibody, ODT1 antibody, STHAGX1 antibody, XHED antibody, XLHED antibody, si:ch73-223d24.5 antibody, Ed1 antibody, Eda-A1 antibody, Eda-A2 antibody, Ta antibody, tabby antibody, RGD1563178 antibody, ectodysplasin A antibody, ectodysplasin-A antibody, EDA antibody, eda antibody, Eda antibody
- Background
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EDA is a type II membrane protein that can be cleaved by furin to produce a secreted form. It belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Alias Symbols: ED1, ED1-A1, ED1-A2, EDA1, EDA2, HED, XHED, XLHED, ODT1, STHAGX1
Protein Interaction Partner: OSTCP1, OSTC, NIPAL3, GIMAP5, SEC22A, LEPROTL1, DOLK, PLN, MAL, EMP3, CYB561, ATP6V0C, EDAR, EDA, EDA2R, FURIN,
Protein Size: 389 - Molecular Weight
- 41 kDa
- Gene ID
- 1896
- NCBI Accession
- NM_001005609, NP_001005609
- UniProt
- B7ZLU4
- Pathways
- Tube Formation
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