FMO3 antibody (N-Term)

Catalog No. ABIN2781862

Product Details anti-FMO3 Antibody

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FMO3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: FMHNSKIQEY IIAFAKEKNL LKYIQFKTFV SSVNKHPDFA TTGQWDVTTE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 90%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FMO3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FMO3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 532 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FMO3 antibody (ABIN2781862)

Ganti, Skapek, Zhang, Fuller, Wu, Billups, Breitfeld, Dalton, Meyer, Khoury: "Expression and genomic status of EGFR and ErbB-2 in alveolar and embryonal rhabdomyosarcoma." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 19, Issue 9, pp. 1213-20, (2006) (PubMed).

Target Details for FMO3

Target: FMO3 (Flavin Containing Monooxygenase 3 (FMO3))

Alternative Name: FMO3 (FMO3 Products)

Synonyms: MGC107820 antibody, FMOII antibody, TMAU antibody, dJ127D3.1 antibody, FM03 antibody, AW111792 antibody, flavin containing monooxygenase 3 antibody, flavin containing monooxygenase 3 L homeolog antibody, FMO3 antibody, fmo3 antibody, fmo3.L antibody, Fmo3 antibody

Background: FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It acts on TMA to produce TMA-N-oxide.
Alias Symbols: FMOII, MGC34400, dJ127D3.1, TMAU
Protein Size: 532

Molecular Weight: 59 kDa

Gene ID: 2328

NCBI Accession: NM_001002294, NP_001002294

UniProt: P31513