PPIB antibody (N-Term)

Catalog No. ABIN502505

Product Details anti-PPIB Antibody

Target: PPIB (Cyclophilin B (PPIB))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KKKGPKVTVK VYFDLRIGDE DVGRVIFGLF GKTVPKTVDN FVALATGEKG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%

Characteristics: This is a rabbit polyclonal antibody against PPIB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPIB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 216 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIB

Target: PPIB (Cyclophilin B (PPIB))

Alternative Name: PPIB (PPIB Products)

Background: PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CYP-S1, CYPB, MGC14109, MGC2224, SCYLP, OI9
Protein Interaction Partner: BANP, UBQLN1, SGTA, PEX19, UBC, MDM2, DDIT3, WWOX, SUZ12, EED, BMI1, rev, RRM1, PPP5C, PFKP, GAPDH, HECW2, FBXO6, UBD, CFTR, ATP12A, VKORC1, OS9, MAGT1, SUGP1, LSM4, TIMM44, SCO2, ZC3H11A, UBL4A, RBMS1, RANGAP1, PCBP2, P4HB, HSPA5, PDIA3, DHX9, ACAA1, MRP
Protein Size: 216

Molecular Weight: 21 kDa

Gene ID: 5479

NCBI Accession: NM_000942, NP_000933

UniProt: P23284