HSD3B2 antibody (N-Term)

Catalog No. ABIN2781776

Product Details anti-HSD3B2 Antibody

Target: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD3B2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GWSCLVTGAG GLLGQRIVRL LVEEKELKEI RALDKAFRPE LREEFSKLQN

Predicted Reactivity: Cow: 85%, Dog: 93%, Goat: 85%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rat: 86%, Sheep: 85%

Characteristics: This is a rabbit polyclonal antibody against HSD3B2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSD3B2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 372 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HSD3B2

Target: HSD3B2 (Hydroxy-delta-5-Steroid Dehydrogenase, 3 beta- and Steroid delta-Isomerase 2 (HSD3B2))

Alternative Name: HSD3B2 (HSD3B2 Products)

Synonyms: HSD3B antibody, HSDB antibody, SDR11E2 antibody, Hsd3b1 antibody, 3b-HSD antibody, HSD3B1 antibody, hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 antibody, HSD3B2 antibody, Hsd3b2 antibody

Background: 3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids.
Alias Symbols: HSDB, HSDB3, HSD3B, SDR11E2
Protein Interaction Partner: ATP4A,
Protein Size: 372

Molecular Weight: 42 kDa

Gene ID: 3284

NCBI Accession: NM_000198, NP_000189

UniProt: P26439

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis