CYBA antibody (Middle Region)

Catalog No. ABIN2781765

Product Details anti-CYBA Antibody

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse, Cow, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYBA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TILGTACLAI ASGIYLLAAV RGEQWTPIEP KPRERPQIGG TIKQPPSNPP

Predicted Reactivity: Cow: 93%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%, Sheep: 93%

Characteristics: This is a rabbit polyclonal antibody against CYBA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYBA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 195 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYBA

Target: CYBA (Cytochrome B-245, alpha Polypeptide (CYBA))

Alternative Name: CYBA (CYBA Products)

Synonyms: zgc:66077 antibody, MGC80750 antibody, CYBA antibody, p22-phox antibody, p22phox antibody, p22-PHOX antibody, b558 antibody, nmf333 antibody, P22-PHOX antibody, cytochrome b-245, alpha polypeptide antibody, cytochrome b-245 alpha polypeptide L homeolog antibody, cytochrome b-245 alpha polypeptide antibody, cytochrome b-245 light chain-like antibody, cytochrome b-245 alpha chain antibody, p22-phox antibody, cyba antibody, cyba.L antibody, CYBA antibody, LOC101328418 antibody, Cyba antibody

Background: Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated
Alias Symbols: p22-PHOX
Protein Interaction Partner: RBPMS, PSMA3, UPF2, RCHY1, UBC, MDFI, CPT1A, NCF1, VHL, RAC1, NCF4, CYBB, NOX1, NCF2,
Protein Size: 195

Molecular Weight: 21 kDa

Gene ID: 1535

NCBI Accession: NM_000101, NP_000092

UniProt: P13498

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis