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Butyrylcholinesterase antibody (N-Term)

BCHE Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Sheep, Guinea Pig, Pig, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781762
  • Target See all Butyrylcholinesterase (BCHE) Antibodies
    Butyrylcholinesterase (BCHE)
    Binding Specificity
    • 15
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Dog, Rat, Cow, Horse, Sheep, Guinea Pig, Pig, Rabbit
    Host
    • 55
    • 21
    Rabbit
    Clonality
    • 54
    • 22
    Polyclonal
    Conjugate
    • 30
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Butyrylcholinesterase antibody is un-conjugated
    Application
    • 59
    • 26
    • 22
    • 13
    • 12
    • 9
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    SSLHVYDGKF LARVERVIVV SMNYRVGALG FLALPGNPEA PGNMGLFDQQ
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
    Characteristics
    This is a rabbit polyclonal antibody against BCHE. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human BCHE
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    Discover our top product BCHE Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 602 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mizukami, Akatsu, Abrahamson, Mi, Ikonomovic: "Immunohistochemical analysis of hippocampal butyrylcholinesterase: Implications for regional vulnerability in Alzheimer's disease." in: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 36, Issue 2, pp. 135-45, (2016) (PubMed).

  • Target
    Butyrylcholinesterase (BCHE)
    Alternative Name
    BCHE (BCHE Products)
    Synonyms
    che antibody, che1 antibody, bche antibody, cholinesterase antibody, CHE1 antibody, CHE2 antibody, E1 antibody, C730038G20Rik antibody, butyrylcholinesterase L homeolog antibody, butyrylcholinesterase antibody, bche.L antibody, bche antibody, BCHE antibody, Bche antibody
    Background
    Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. In the absence of the relaxant, the homozygote is at no known disadvantage.
    Alias Symbols: CHE1, E1
    Protein Interaction Partner: COLQ, BCHE,
    Protein Size: 602
    Molecular Weight
    68 kDa
    Gene ID
    590
    NCBI Accession
    NM_000055, NP_000046
    UniProt
    P06276
    Pathways
    Peptide Hormone Metabolism
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