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SLC26A5 antibody (Middle Region)

SLC26A5 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781751
  • Target See all SLC26A5 Antibodies
    SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 18
    • 13
    • 13
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit
    Host
    • 15
    • 2
    • 1
    Rabbit
    Clonality
    • 17
    • 1
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC26A5 antibody is un-conjugated
    Application
    • 9
    • 8
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    FSVTISMAKT LANKHGYQVD GNQELIALGL CNSIGSLFQT FSISCSLSRS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLC26A5. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SLC26A5
    Top Product
    Discover our top product SLC26A5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 744 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SLC26A5 (Solute Carrier Family 26, Member 5 (Prestin) (SLC26A5))
    Alternative Name
    SLC26A5 (SLC26A5 Products)
    Synonyms
    pres antibody, fb73d12 antibody, fb74g12 antibody, wu:fb73d12 antibody, wu:fb74g12 antibody, DFNB61 antibody, PRES antibody, Pres antibody, prestin antibody, solute carrier family 26 (anion exchanger), member 5 antibody, solute carrier family 26 member 5 antibody, solute carrier family 26, member 5 antibody, slc26a5 antibody, SLC26A5 antibody, Slc26a5 antibody
    Background
    SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
    Alias Symbols: DFNB61, MGC118886, MGC118887, MGC118888, MGC118889, PRES
    Protein Size: 744
    Molecular Weight
    81 kDa
    Gene ID
    375611
    NCBI Accession
    NM_198999, NP_945350
    UniProt
    P58743
    Pathways
    Sensory Perception of Sound, Dicarboxylic Acid Transport
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