SLC39A4 antibody (N-Term)
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- Target See all SLC39A4 Antibodies
- SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rabbit, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SLC39A4 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASLVSLELGL LLAVLVVTAT ASPPAGLLSL LTSGQGALDQ EALGGLLNTL
- Predicted Reactivity
- Cow: 86%, Human: 100%, Rabbit: 86%
- Characteristics
- This is a rabbit polyclonal antibody against SLC39A4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4
- Top Product
- Discover our top product SLC39A4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 647 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).
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Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).
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- Target
- SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))
- Alternative Name
- SLC39A4 (SLC39A4 Products)
- Synonyms
- AEZ antibody, AWMS2 antibody, ZIP4 antibody, 1600025H15Rik antibody, AU041686 antibody, solute carrier family 39 member 4 antibody, solute carrier family 39 (zinc transporter), member 4 antibody, SLC39A4 antibody, slc39a4 antibody, Slc39a4 antibody
- Background
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SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AEZ, FLJ20327, MGC74741, ZIP4, AWMS2
Protein Interaction Partner: UBC,
Protein Size: 647 - Molecular Weight
- 68 kDa
- Gene ID
- 55630
- NCBI Accession
- NM_130849, NP_570901
- UniProt
- Q6P5W5
- Pathways
- Transition Metal Ion Homeostasis, Autophagy
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