ORCTL-2/SLC22A18 antibody (N-Term)

Catalog No. ABIN2781574

Product Details anti-ORCTL-2/SLC22A18 Antibody

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORCTL-2/SLC22A18 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AASSPALPGV YLLFASRLPG ALMHTLPAAQ MVITDLSAPE ERPAALGRLG

Predicted Reactivity: Cow: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against SLC22A18. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC22A18

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 424 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ORCTL-2/SLC22A18

Target: ORCTL-2/SLC22A18 (SLC22A18) (Solute Carrier Family 22 Member 18 (SLC22A18))

Alternative Name: SLC22A18 (SLC22A18 Products)

Synonyms: MGC123168 antibody, zgc:123168 antibody, BWR1A antibody, BWSCR1A antibody, HET antibody, IMPT1 antibody, ITM antibody, ORCTL2 antibody, SLC22A1L antibody, TSSC5 antibody, p45-BWR1A antibody, AW260131 antibody, Impt1 antibody, Orctl2 antibody, Slc22a1l antibody, solute carrier family 22, member 18 antibody, solute carrier family 22 member 18 antibody, solute carrier family 22 (organic cation transporter), member 18 antibody, slc22a18 antibody, SLC22A18 antibody, Slc22a18 antibody

Background: This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney.This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region as well as the transport of chloroquine- and quinidine-related compounds in the kidney. Two alternative transcripts encoding the same isoform have been described.
Alias Symbols: BWR1A, BWSCR1A, DKFZp667A184, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A
Protein Interaction Partner: RNF167, UBC,
Protein Size: 424

Molecular Weight: 45 kDa

Gene ID: 5002

NCBI Accession: NM_002555, NP_002546

UniProt: Q96BI1