GOT2 antibody (C-Term)

Catalog No. ABIN2781301

Product Details anti-GOT2 Antibody

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AILNTPDLRK QWLQEVKVMA DRIIGMRTQL VSNLKKEGST HNWQHITDQI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GOT2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GOT2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 430 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GOT2 antibody (ABIN2781301)

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2 (GOT2 Products)

Synonyms: KAT4 antibody, KATIV antibody, mitAAT antibody, AI789014 antibody, Got-1 antibody, cAspAT antibody, cCAT antibody, AL022787 antibody, FABP-pm antibody, Got-2 antibody, mAspAT antibody, ASPATA antibody, got2 antibody, zgc:66329 antibody, fj40h07 antibody, wu:fj40h07 antibody, zgc:56425 antibody, glutamic-oxaloacetic transaminase 2 antibody, glutamic-oxaloacetic transaminase 1, soluble antibody, glutamatic-oxaloacetic transaminase 2, mitochondrial antibody, glutamic-oxaloacetic transaminase 2a, mitochondrial antibody, glutamic-oxaloacetic transaminase 2 L homeolog antibody, Aspartate amino transferase activity antibody, glutamic-oxaloacetic transaminase 2b, mitochondrial antibody, GOT2 antibody, got2 antibody, Got1 antibody, Got2 antibody, got2a antibody, got2.L antibody, AST antibody, got2b antibody

Background: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
Alias Symbols: FLJ40994, kat4, kativ, mitaat, KAT4, KATIV, mitAAT
Protein Interaction Partner: FUS, UBC, NEDD8, MDM2, CDK2, CCL21, GLRX, GAPDH, APCS, AI837181, HDAC5, PSMD4, THOC7, ZDHHC6, GLUD1, HSPA8, PC, MDH2, CTNNBIP1, MPG,
Protein Size: 430

Molecular Weight: 45 kDa

Gene ID: 2806

NCBI Accession: NM_002080, NP_002071

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process