CBLL1 antibody (C-Term)

Catalog No. ABIN2781231

Product Details anti-CBLL1 Antibody

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBLL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PFTQPGGMSP GIWPAPRGPP PPPRLQGPPS QTPLPGPHHP DQTRYRPYYQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CBLL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBLL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 491 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-CBLL1 antibody (ABIN2781231)

Horiuchi, Kawamura, Iwanari, Ohashi, Naito, Kodama, Hamakubo: "Identification of Wilms' tumor 1-associating protein complex and its role in alternative splicing and the cell cycle." in: The Journal of biological chemistry, Vol. 288, Issue 46, pp. 33292-302, (2013) (PubMed).

Target Details for CBLL1

Target: CBLL1 (Cas-Br-M (Murine) Ecotropic Retroviral Transforming Sequence-Like 1 (CBLL1))

Alternative Name: CBLL1 (CBLL1 Products)

Synonyms: HAKAI antibody, RNF188 antibody, zgc:55308 antibody, CBLL1 antibody, AI467391 antibody, Hakai antibody, c-Cbl-like antibody, cbll1 antibody, hakai antibody, rnf188 antibody, Cbl proto-oncogene like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase S homeolog antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase antibody, Casitas B-lineage lymphoma-like 1 antibody, Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase L homeolog antibody, CBLL1 antibody, cbll1.S antibody, Cbll1 antibody, cbll1 antibody, cbll1.L antibody

Background: Epithelial cell cadherin is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. CBLL1 is an E3 ubiquitin ligase that mediates ubiquitination of the CDH1 complex.Epithelial cell cadherin (CDH1, MIM 192090) is endocytosed as a consequence of tyrosine phosphorylation and ubiquitination. HAKAI is an E3 ubiquitin ligase (see UBE3A, MIM 601623) that mediates ubiquitination of the CDH1 complex.[supplied by OMIM].
Alias Symbols: HAKAI, RNF188
Protein Interaction Partner: DGCR6, SUMO1, UBC, CDH1, RNF2, YWHAQ, SFPQ, Cbll1, ESR1, CTTN, DOK1, SRC, CDC42,
Protein Size: 491

Molecular Weight: 55 kDa

Gene ID: 79872

NCBI Accession: NM_024814, NP_079090

UniProt: Q75N03