LASS4 antibody (N-Term)

Catalog No. ABIN2781212

Product Details anti-LASS4 Antibody

Target: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Pig, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LASS4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MLSSFNEWFW QDRFWLPPNV TWTELEDRDG RVYPHPQDLL AALPLALVLL

Predicted Reactivity: Dog: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against LASS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LASS4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 394 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-LASS4 antibody (ABIN2781212)

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Target Details for LASS4

Target: LASS4 (CERS4) (Ceramide Synthase 4 (CERS4))

Alternative Name: LASS4 (CERS4 Products)

Synonyms: trh1 antibody, 2900019C14Rik antibody, Lass4 antibody, Trh1 antibody, LASS4 antibody, ceramide synthase 4a antibody, ceramide synthase 4 antibody, ceramide synthase 4-like antibody, cers4a antibody, Cers4 antibody, CERS4 antibody, CERS4L antibody

Background: LASS4 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells it is involved in the production of sphingolipids containing different fatty acid donnors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.
Alias Symbols: CerS4, FLJ12089, Trh1, LASS4
Protein Size: 394

Molecular Weight: 46 kDa

Gene ID: 79603

NCBI Accession: NM_024552, NP_078828

UniProt: Q9HA82