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HOXB8 antibody (N-Term)

HOXB8 Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Horse, Sheep WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781203
  • Target See all HOXB8 Antibodies
    HOXB8 (Homeobox B8 (HOXB8))
    Binding Specificity
    • 15
    • 14
    • 11
    • 9
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Horse, Sheep
    Host
    • 53
    • 1
    Rabbit
    Clonality
    • 54
    Polyclonal
    Conjugate
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HOXB8 antibody is un-conjugated
    Application
    • 47
    • 24
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    MSSYFVNSLF SKYKTGESLR PNYYDCGFAQ DLGGRPTVVY GPSSGGSFQH
    Predicted Reactivity
    Cow: 79%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 79%
    Characteristics
    This is a rabbit polyclonal antibody against HOXB8. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB8
    Top Product
    Discover our top product HOXB8 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 243 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HOXB8 (Homeobox B8 (HOXB8))
    Alternative Name
    HOXB8 (HOXB8 Products)
    Synonyms
    HOX2 antibody, HOX2D antibody, Hox-2.4 antibody, Hox2r1a antibody, hoxa8 antibody, z-9 antibody, HBX antibody, HBX24 antibody, HOXB8 antibody, homeobox B8 antibody, homeobox protein Hox-B8 antibody, homeo box B8 antibody, homeobox B8b antibody, porcine homeobox antibody, HOXB8 antibody, Hoxb8 antibody, LOC785855 antibody, hoxb8b antibody, HOX-2.4 antibody
    Background
    HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
    Alias Symbols: HOX2, HOX2D, Hox-2.4
    Protein Interaction Partner: PBX3, PBX2, PBX1, MEIS1,
    Protein Size: 243
    Molecular Weight
    28 kDa
    Gene ID
    3218
    NCBI Accession
    NM_024016, NP_076921
    UniProt
    P17481
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