SOX17 antibody (Middle Region)

Catalog No. ABIN2781184

Product Details anti-SOX17 Antibody

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RTEFEQYLHF VCKPEMGLPY QGHDSGVNLP DSHGAISSVV SDASSAVYYC

Predicted Reactivity: Dog: 86%, Guinea Pig: 93%, Human: 100%, Mouse: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against SOX17. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX17

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 414 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SOX17 antibody (ABIN2781184)

Kallas, Pook, Trei, Maimets: "SOX2 Is Regulated Differently from NANOG and OCT4 in Human Embryonic Stem Cells during Early Differentiation Initiated with Sodium Butyrate." in: Stem cells international, Vol. 2014, pp. 298163, (2014) (PubMed).

Target Details for SOX17

Target: SOX17 (SRY (Sex Determining Region Y)-Box 17 (SOX17))

Alternative Name: SOX17 (SOX17 Products)

Synonyms: VUR3 antibody, SOX17 antibody, Sox17alpha antibody, Xsox17 antibody, Xsox17-alpha antibody, Xsox17alpha antibody, sox17-alpha antibody, tSox17alpha antibody, xSox17alpha1 antibody, xSox17alpha2 antibody, xsox17a antibody, sox17 antibody, sox7/17 antibody, Sox antibody, SRY-box 17 antibody, SRY (sex determining region Y)-box 17 antibody, SRY box 17 antibody, SRY-box 17 alpha antibody, sox7/17 protein antibody, SOX17 antibody, sox17 antibody, Sox17 antibody, sox17a antibody, sox7/17 antibody

Background: The SOX17 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Alias Symbols: FLJ22252, VUR3
Protein Interaction Partner: CTNNB1,
Protein Size: 414

Molecular Weight: 44 kDa

Gene ID: 64321

NCBI Accession: NM_022454, NP_071899

UniProt: Q9H6I2