SSX3 antibody (N-Term)

Catalog No. ABIN2781134

Product Details anti-SSX3 Antibody

Target: SSX3 (Synovial Sarcoma, X Breakpoint 3 (SSX3))

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LCPPGKPTTS EKINMISGPK RGEHAWTHRL RERKQLVIYE EISDPEEDDE

Predicted Reactivity: Cow: 80%, Dog: 85%, Guinea Pig: 83%, Horse: 83%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SSX3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SSX3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 188 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSX3

Target: SSX3 (Synovial Sarcoma, X Breakpoint 3 (SSX3))

Alternative Name: SSX3 (SSX3 Products)

Synonyms: CT5.3 antibody, SSX2 antibody, SSX3 antibody, SSX family member 3 antibody, protein SSX2 antibody, SSX3 antibody, LOC741661 antibody

Background: The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CT5.3, MGC119054, MGC14495
Protein Interaction Partner: MIPOL1, SSX2IP, CMTM5, CEP70, CEP63, RHOJ, AGTRAP, MED4, MEOX2, ZSCAN1, ZNF496, PCBD2, ZBTB3, ZBTB25, DDIT3,
Protein Size: 188

Molecular Weight: 22 kDa

Gene ID: 10214

NCBI Accession: NM_021014, NP_066294

UniProt: Q7RTT3