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MNT antibody (N-Term)

MNT Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Pig, Horse, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781100
  • Target See all MNT Antibodies
    MNT (MNT, MAX Dimerization Protein (MNT))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 21
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Rabbit, Cow, Dog, Pig, Horse, Saccharomyces cerevisiae
    Host
    • 19
    • 2
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MNT antibody is un-conjugated
    Application
    • 15
    • 6
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SIETLLEAAR FLEWQAQQQQ RAREEQERLR LEQEREQEQK KANSLARLAH
    Predicted Reactivity
    Cow: 93%, Dog: 93%, Horse: 80%, Human: 100%, Mouse: 93%, Pig: 80%, Rabbit: 93%, Rat: 93%, Yeast: 92%
    Characteristics
    This is a rabbit polyclonal antibody against MNT. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human MNT
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    Discover our top product MNT Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 582 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MNT (MNT, MAX Dimerization Protein (MNT))
    Alternative Name
    MNT (MNT Products)
    Synonyms
    MAD6 antibody, MXD6 antibody, ROX antibody, bHLHd3 antibody, etID309773.22 antibody, fb16b12 antibody, fb55f03 antibody, wu:fb16b12 antibody, wu:fb55f03 antibody, wu:fd06a08 antibody, wu:fz74f10 antibody, Rox antibody, Mnt antibody, zgc:165490 antibody, mnt antibody, rox antibody, MGC98824 antibody, MAX network transcriptional repressor antibody, max interactor 1, dimerization protein antibody, max binding protein antibody, MAX network transcriptional repressor b antibody, MAX network transcriptional repressor L homeolog antibody, MNT antibody, mxi1 antibody, Mnt antibody, mntb antibody, mnt.L antibody
    Background
    The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. MNT is a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain.The Myc/Max/Mad network comprises a group of transcription factors that co-interact to regulate gene-specific transcriptional activation or repression. This gene encodes a protein member of the Myc/Max/Mad network. This protein has a basic-Helix-Loop-Helix-zipper domain (bHLHzip) with which it binds the canonical DNA sequence CANNTG, known as the E box, following heterodimerization with Max proteins. This protein is likely a transcriptional repressor and an antagonist of Myc-dependent transcriptional activation and cell growth. This protein represses transcription by binding to DNA binding proteins at its N-terminal Sin3-interaction domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: MAD6, MXD6, ROX, bHLHd3
    Protein Interaction Partner: Dlg4, ELAVL1, CEBPA, MAX, MAD1L1, MYC, HDAC1, SIN3A, MNT, MLX, HMGB1,
    Protein Size: 582
    Molecular Weight
    62 kDa
    Gene ID
    4335
    NCBI Accession
    NM_020310, NP_064706
    UniProt
    Q99583
    Pathways
    Chromatin Binding, Regulation of Muscle Cell Differentiation
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