ARNTL2 antibody (N-Term)

Catalog No. ABIN2781092

Product Details anti-ARNTL2 Antibody

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PTAMGSFSSH MTEFPRKRKG SDSDPSQSGI MTEKVVEKLS QNPLTYLLST

Predicted Reactivity: Dog: 86%, Human: 100%, Mouse: 77%

Characteristics: This is a rabbit polyclonal antibody against ARNTL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 636 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARNTL2

Target: ARNTL2 (Aryl Hydrocarbon Receptor Nuclear Translocator-Like 2 (ARNTL2))

Alternative Name: ARNTL2 (ARNTL2 Products)

Synonyms: BMAL2 antibody, CLIF antibody, MOP9 antibody, PASD9 antibody, bHLHe6 antibody, bmal2 antibody, wu:fj90c09 antibody, 4632430A05Rik antibody, Arnt4 antibody, Bmal2 antibody, ARNTL2 antibody, aryl hydrocarbon receptor nuclear translocator like 2 antibody, aryl hydrocarbon receptor nuclear translocator-like 2 antibody, ARNTL2 antibody, arntl2 antibody, Arntl2 antibody

Background: ARNTL2-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription. Also, in umbilical vein endothelial cells, ARNTL2 activates SERPINE1 through E-box sites. This transactivation is inhibited by PER2 and CRY1.
Alias Symbols: BMAL2, CLIF, MGC149671, MGC149672, MOP9, PASD9, bHLHe6
Protein Interaction Partner: NPAS2, UBC, EPAS1, CLOCK,
Protein Size: 636

Molecular Weight: 71 kDa

Gene ID: 56938

NCBI Accession: NM_020183, NP_064568

UniProt: Q8WYA1

Pathways: Photoperiodism