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ZNF446 antibody (C-Term)

ZNF446 Reactivity: Human, Rat, Guinea Pig, Dog, Mouse, Cow, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2781046
  • Target See all ZNF446 Antibodies
    ZNF446 (Zinc Finger Protein 446 (ZNF446))
    Binding Specificity
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    Human, Rat, Guinea Pig, Dog, Mouse, Cow, Horse, Rabbit
    Host
    • 15
    • 2
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNF446 antibody is un-conjugated
    Application
    • 10
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Sequence
    SYPCEECGCS FSWKSQLVIH RKSHTGQRRH FCSDCGRAFD WKSQLVIHRK
    Predicted Reactivity
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF446
    Top Product
    Discover our top product ZNF446 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 450 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    ZNF446 (Zinc Finger Protein 446 (ZNF446))
    Alternative Name
    ZNF446 (ZNF446 Products)
    Synonyms
    ZKSCAN20 antibody, ZSCAN30 antibody, ZSCAN52 antibody, AA120513 antibody, AV306632 antibody, A930031C22 antibody, A630035I11Rik antibody, ZNF446 antibody, DKFZp468H2122 antibody, C230097I24Rik antibody, Gm754 antibody, Zfp397os antibody, zinc finger protein 446 antibody, zinc finger and SCAN domain containing 30 antibody, ZNF446 antibody, Zfp446 antibody, Znf446 antibody, Zscan30 antibody
    Background
    ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-1, suggesting that the ZNF446 protein may act as a transcriptional repressor in mitogen-activated protein kinase (MAPK) signaling pathway to mediate cellular functions.
    Alias Symbols: ZSCAN30, ZKSCAN20
    Protein Interaction Partner: NOTCH2NL, KRTAP10-3, ZSCAN22, ZNF396, KRT40, ZNF496, PGBD1, LZTS2, ZNF397, ZSCAN16, ZKSCAN7, ZNF446, ZSCAN32, ZNF232, ZSCAN9, ZNF165, ZSCAN21, ZNF24, TRIM27, PIN1, DGCR6, ACTN2, FHL5, DGCR6L, SUFU, ZNF263,
    Protein Size: 450
    Molecular Weight
    49 kDa
    Gene ID
    55663
    NCBI Accession
    NM_017908, NP_060378
    UniProt
    Q9NWS9
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