ZNF446 antibody (N-Term)

Catalog No. ABIN2781045

Product Details anti-ZNF446 Antibody

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF446 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MPSPLGPPCL PVMDPETTLE EPETARLRFR GFCYQEVAGP REALARLREL

Predicted Reactivity: Human: 100%, Mouse: 90%, Rat: 90%

Characteristics: This is a rabbit polyclonal antibody against ZNF446. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF446

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 450 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF446

Target: ZNF446 (Zinc Finger Protein 446 (ZNF446))

Alternative Name: ZNF446 (ZNF446 Products)

Synonyms: ZKSCAN20 antibody, ZSCAN30 antibody, ZSCAN52 antibody, AA120513 antibody, AV306632 antibody, A930031C22 antibody, A630035I11Rik antibody, ZNF446 antibody, DKFZp468H2122 antibody, C230097I24Rik antibody, Gm754 antibody, Zfp397os antibody, zinc finger protein 446 antibody, zinc finger and SCAN domain containing 30 antibody, ZNF446 antibody, Zfp446 antibody, Znf446 antibody, Zscan30 antibody

Background: ZNF446 contains a KRAB and three C(2)H(2) zinc fingers. ZNF446 is a transcription repressor when fused to GAL4 DNA-binding domain and co-transfected with VP-16. Overexpression of ZNF446 in COS-7 cells inhibits the transcriptional activities of SRE and AP-
Alias Symbols: FLJ20626, ZKSCAN20, ZSCAN30
Protein Interaction Partner: NOTCH2NL, KRTAP10-3, ZSCAN22, ZNF396, KRT40, ZNF496, PGBD1, LZTS2, ZNF397, ZSCAN16, ZKSCAN7, ZNF446, ZSCAN32, ZNF232, ZSCAN9, ZNF165, ZSCAN21, ZNF24, TRIM27, PIN1, DGCR6, ACTN2, FHL5, DGCR6L, SUFU, ZNF263,
Protein Size: 450

Molecular Weight: 49 kDa

Gene ID: 55663

NCBI Accession: NM_017908, NP_060378

UniProt: Q9NWS9