NKRF antibody (Middle Region)

Catalog No. ABIN2781032

Product Details anti-NKRF Antibody

Target: NKRF (NFKB Repressing Factor (NKRF))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKRF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QKYGLKSKSH GVGHDRYLVV GRKRRKEDLL DQLKQEGQVG HYELVMPQAN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NKRF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NKRF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 690 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NKRF

Target: NKRF (NFKB Repressing Factor (NKRF))

Alternative Name: NKRF (NKRF Products)

Synonyms: NKRF antibody, NRF antibody, nrf antibody, itba4 antibody, 9430034D17Rik antibody, AW124770 antibody, C80287 antibody, ITBA4 antibody, RGD1563950 antibody, NFKB repressing factor antibody, NFKB repressing factor L homeolog antibody, NF-kappaB repressing factor antibody, NFKB repressing factor-like antibody, NKRF antibody, nkrf antibody, nkrf.L antibody, Nkrf antibody, Nkrfl antibody

Background: NKRF is a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. NKRF localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. This gene encodes a transcription factor that interacts with specific negative regulatory elements (NREs) to mediate transcriptional repression of certain NK-kappa-B-responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm.
Alias Symbols: ITBA4, NRF
Protein Interaction Partner: STAU1, UBC, XRN2, BMI1, TARDBP, BARD1, CAND1, COPS5, CUL1, CUL3, SIRT7, HNRNPA1, SUMO2, VHL, DHX58, PRKRA, SUMO1, HMOX2, BCL6, REL, RELA, NFKB2, NFKB1,
Protein Size: 690

Molecular Weight: 78 kDa

Gene ID: 55922

NCBI Accession: NM_017544, NP_060014

UniProt: O15226