KLHL5 antibody (N-Term)

Catalog No. ABIN2780990

Product Details anti-KLHL5 Antibody

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLHL5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSGSRKEFDV KQILKIRWRW FGHQASSPNS TVDSQQGEFW NRGQTGANGG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against KLHL5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human KLHL5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 709 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-KLHL5 antibody (ABIN2780990)

Nagalla, Shaw, Kong, Kondkar, Edelstein, Ma, Chen, McKnight, López, Yang, Jin, Bray, Leal, Dong, Bray: "Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity." in: Blood, Vol. 117, Issue 19, pp. 5189-97, (2011) (PubMed).

Target Details for KLHL5

Target: KLHL5 (Kelch-Like 5 (KLHL5))

Alternative Name: KLHL5 (KLHL5 Products)

Synonyms: 1300013C10Rik antibody, kelch-like 5 antibody, kelch like family member 5 antibody, kelch-like family member 5 antibody, Klhl5 antibody, KLHL5 antibody, klhl5 antibody

Background: The kelch-repeat protein family is a recently found new kind of actin-binding protein. It is characterized by tandemly arranged motifs of about 50 amino acids. Most members of the kelch-repeat family were cytoskeletal proteins implicated in various cellular processes, such as actin cytoskeleton interaction, cytoplasmic sequestration of transcription factors and cell morphology. During the large-scale sequencing analysis of a human fetal brain cDNA library we found a novel kelch-like protein gene 5, KLHL5, KLHL5 has high identity with Drosophila kelch protein and many other family members. A novel splicing variants of KLHL5, named KLHL5b and the expression pattern of KLHL5b in many tissues.
Alias Symbols: -
Protein Interaction Partner: FUS, CUL3, UBC, MAP1LC3B, GABARAPL2, TK1, SMN1,
Protein Size: 709

Molecular Weight: 79 kDa

Gene ID: 51088

NCBI Accession: NM_001007075, NP_001007076

UniProt: Q96PQ7