NT5C antibody (C-Term)

Catalog No. ABIN2780936

Product Details anti-NT5C Antibody

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NT5C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QEETPSWEHI LFTCCHNRHL VLPPTRRRLL SWSDNWREIL DSKRGAAQRE

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against NT5C. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 201 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NT5C

Target: NT5C (5',3'-Nucleotidase, Cytosolic (NT5C))

Alternative Name: NT5C (NT5C Products)

Synonyms: DNT antibody, DNT1 antibody, P5N2 antibody, PN-I antibody, PN-II antibody, UMPH2 antibody, cdN antibody, dNT-1 antibody, Dnt antibody, Dnt1 antibody, Umph-2 antibody, Umph2 antibody, 5', 3'-nucleotidase, cytosolic antibody, 5',3'-nucleotidase, cytosolic antibody, NT5C antibody, Nt5c antibody

Background: This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: DNT, DNT1, P5N2, PN-I, PN-II, UMPH2, cdN, dNT-1
Protein Interaction Partner: UBC, NT5C,
Protein Size: 201

Molecular Weight: 23 kDa

Gene ID: 30833

NCBI Accession: NM_014595, NP_055410

UniProt: Q8TCD5