VSX1 antibody (N-Term)

Catalog No. ABIN2780933

Product Details anti-VSX1 Antibody

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Binding Specificity: N-Term

Reactivity: Human, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTGRDSLSDG RTSSRALVPG GSPRGSRPRG FAITDLLGLE AELPAPAGPG

Predicted Reactivity: Cow: 79%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against VSX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VSX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 239 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VSX1

Target: VSX1 (Visual System Homeobox 1 (VSX1))

Alternative Name: VSX1 (VSX1 Products)

Synonyms: VSX1 antibody, CAASDS antibody, KTCN antibody, KTCN1 antibody, PPCD antibody, PPD antibody, RINX antibody, CHX10-1 antibody, CHX10-like antibody, visual system homeobox 1 antibody, visual system homeobox 1 L homeolog antibody, visual system homeobox 1 homolog, chx10-like antibody, Vsx1 antibody, VSX1 antibody, Tsp_01485 antibody, vsx1.L antibody, vsx1 antibody

Background: VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. VSX1 may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. The protein encoded by this gene contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy (PPCD) and keratoconus. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: PPD, KTCN, PPCD, RINX, KTCN1, CAASDS
Protein Size: 239

Molecular Weight: 25 kDa

Gene ID: 30813

NCBI Accession: NM_199425, NP_955457