AKAP8L antibody (C-Term)

Catalog No. ABIN2780924

Product Details anti-AKAP8L Antibody

Target: AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKAP8L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: APGAVSPPPP PPPEEEEEGA VPLLGGALQR QIRGIPGLDV EDDEEGGGGA

Predicted Reactivity: Cow: 88%, Dog: 88%, Horse: 87%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against AKAP8L. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AKAP8L

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 646 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AKAP8L

Target: AKAP8L (A Kinase (PRKA) Anchor Protein 8-Like (AKAP8L))

Alternative Name: AKAP8L (AKAP8L Products)

Synonyms: HA95 antibody, HAP95 antibody, NAKAP antibody, NAKAP95 antibody, Nakap95 antibody, zgc:85966 antibody, AKAP8L antibody, A-kinase anchoring protein 8 like antibody, A kinase (PRKA) anchor protein 8-like antibody, A-kinase anchoring protein 8 like L homeolog antibody, AKAP8L antibody, Akap8l antibody, akap8l antibody, akap8l.L antibody

Background: AKAP8L could play a role in constitutive transport element (CTE)-mediated gene expression. It does not seem to be implicated in the binding of regulatory subunit II of PKA. It may be involved in nuclear envelope breakdown and chromatin condensation. It may regulate the initiation phase of DNA replication when associated with TMPO-beta.
Alias Symbols: HA95, HAP95, NAKAP, NAKAP95
Protein Interaction Partner: SUMO2, IRS4, UBC, RNF31, SUZ12, RNF2, BMI1, ANKRD28, HDAC11, ILK, vif, EPAS1, BARD1, CAND1, CUL1, CUL2, CUL3, EBNA-LP, Mis12, MYC, PRPF40A, AKAP8L, DHX9, CDC6, PRKACA, LBR, EMD, TMPO, RNF43, MAGED1, RELA,
Protein Size: 646

Molecular Weight: 72 kDa

Gene ID: 26993

NCBI Accession: NM_014371, NP_055186

UniProt: Q9ULX6

Pathways: SARS-CoV-2 Protein Interactome