ZNF175 antibody (C-Term)

Catalog No. ABIN2780832

Product Details anti-ZNF175 Antibody

Target: ZNF175 (Zinc Finger Protein 175 (ZNF175))

Binding Specificity: C-Term

Reactivity: Human, Cow, Horse, Mouse, Pig, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF175 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QRIHTGERPY VCSECGKAFN NRSNFNKHQT THTRDKSYKC SYSVKGFTKQ

Predicted Reactivity: Cow: 100%, Dog: 85%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 85%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against ZNF175. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ZNF175

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 711 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZNF175 antibody (ABIN2780832)

Carlson, Limoges, Pohlman, Poluektova, Langford, Masliah, Ikezu, Gendelman: "OTK18 expression in brain mononuclear phagocytes parallels the severity of HIV-1 encephalitis." in: Journal of neuroimmunology, Vol. 150, Issue 1-2, pp. 186-98, (2004) (PubMed).

Target Details for ZNF175

Target: ZNF175 (Zinc Finger Protein 175 (ZNF175))

Alternative Name: ZNF175 (ZNF175 Products)

Synonyms: ZNF175 antibody, OTK18 antibody, zinc finger protein 175 antibody, ZNF175 antibody

Background: ZNF175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. As a transcriptional suppressor, this protein plays a role in macrophage control of viral replication during advanced HIV-1 infection.
Alias Symbols: OTK18
Protein Interaction Partner: KRTAP10-7, ZNF250, ZNF264, PSTPIP1, ALAS1, LPXN, UBC, LZTR1, CDC42,
Protein Size: 711

Molecular Weight: 81 kDa

Gene ID: 7728

NCBI Accession: NM_007147, NP_009078

UniProt: Q9Y473