ELL antibody (N-Term)

Catalog No. ABIN2780787

Product Details anti-ELL Antibody

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ELL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GLSCGRVSDG SKVSVFHVKL TDSALRAFES YRARQDSVSL RPSIRFQGSQ

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against ELL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 621 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ELL

Target: ELL (Elongation Factor RNA Polymerase II (ELL))

Alternative Name: ELL (ELL Products)

Synonyms: wu:fc60b11 antibody, zgc:63836 antibody, C19orf17 antibody, ELL1 antibody, MEN antibody, PPP1R68 antibody, Ell1 antibody, Men antibody, elongation factor for RNA polymerase II antibody, elongation factor RNA polymerase II antibody, ELL antibody, ell antibody, Ell antibody

Background: ELL was shown to encode a previously uncharacterized elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by polymerase at multiple sites along the DNA. Functionally, ELL resembles Elongin (SIII), a transcription elongation factor regulated by the product of the von Hippel-Lindau (VHL) tumor suppressor gene.
Alias Symbols: MEN, ELL1, PPP1R68, C19orf17
Protein Interaction Partner: UBC, LOC100363176, SNF8, MCM2, Polr2e, Polr2l, Polr2h, Polr2d, Polr2a, Polr2c, Polr2i, Polr2b, Polr2j, Polr2g, Polr2f, EAF1, ICE2, AFF4, PPP1CA, ICE1, MED26, MLLT3, CDK9, TFPT, KMT2A, MLLT1, USPL1, EAF2, HNRNPU, TP53, ZHX1, SIRT2,
Protein Size: 621

Molecular Weight: 68 kDa

Gene ID: 8178

NCBI Accession: NM_006532, NP_006523

UniProt: P55199