TFEB antibody (C-Term)

Catalog No. ABIN2780786

Product Details anti-TFEB Antibody

Target: TFEB (Transcription Factor EB (TFEB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Goat, Rabbit, Guinea Pig, Saccharomyces cerevisiae, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLSKKDLDLM LLDDSLLPLA SDPLLSTMSP EASKASSRRS SFSMEEGDVL

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Yeast: 100%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against TFEB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFEB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Alternative Name: TFEB (TFEB Products)

Synonyms: TFEB antibody, tcfeb antibody, MGC145796 antibody, alphatfeb antibody, ALPHATFEB antibody, BHLHE35 antibody, TCFEB antibody, Tcfeb antibody, bHLHe35 antibody, transcription factor EB antibody, TFEB antibody, tfeb antibody, Tfeb antibody

Background: TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t(6,11)(p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Alias Symbols: TCFEB, BHLHE35, ALPHATFEB
Protein Interaction Partner: SRPK1, YWHAQ, TFEC, TFE3, MITF,
Protein Size: 476

Molecular Weight: 53 kDa

Gene ID: 7942

NCBI Accession: NM_007162, NP_009093

UniProt: P19484