PEG3 antibody (C-Term)

Catalog No. ABIN2780754

Product Details anti-PEG3 Antibody

Target: PEG3 (Paternally Expressed 3 (PEG3))

Binding Specificity: C-Term

Reactivity: Human, Rat, Mouse, Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEG3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FGECSGYIER ASTSTGGANQ ADEKYFKCDV CGQLFNDRLS LARHQNTHTG

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PEG3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PEG3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1588 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PEG3

Target: PEG3 (Paternally Expressed 3 (PEG3))

Alternative Name: PEG3 (PEG3 Products)

Synonyms: PW1 antibody, ZKSCAN22 antibody, ZNF904 antibody, ZSCAN24 antibody, AL022617 antibody, ASF-1 antibody, End4 antibody, Gcap4 antibody, Pw1 antibody, Zfp102 antibody, mKIAA0287 antibody, PEG3 antibody, paternally expressed 3 antibody, paternally-expressed gene 3 protein antibody, PEG3 antibody, Peg3 antibody, LOC100448879 antibody

Background: PEG3 induces apoptosis in cooperation with SIAH1A and acts as a mediator between TP53/p53 and BAX in a neuronal death pathway that is activated by DNA damage. PEG3 acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. PEG3 also possesses a tumor suppressing activity in glioma cells.
Alias Symbols: PW1, ZNF904, ZSCAN24
Protein Interaction Partner: PEG3, ALB, USP7, TRAF2, SIAH2, SIAH1, BRCA1,
Protein Size: 1588

Molecular Weight: 181 kDa

Gene ID: 5178

NCBI Accession: NM_006210, NP_006201

UniProt: Q9GZU2