NRF2 antibody (C-Term)
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- Target See all NRF2 (NFE2L2) Antibodies
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NRF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KEKGENDKSL HLLKKQLSTL YLEVFSMLRD EDGKPYSPSE YSLQQTRDGN
- Predicted Reactivity
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against NFE2L2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human NFE2L2
- Top Product
- Discover our top product NFE2L2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 605 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))
- Alternative Name
- NFE2L2 (NFE2L2 Products)
- Synonyms
- Nrf2 antibody, nfe2l2 antibody, wu:fc15g09 antibody, wu:fj67e03 antibody, NF-E2R2 antibody, NRF2 antibody, AI194320 antibody, nuclear factor, erythroid 2-like 2a antibody, nuclear factor, erythroid 2 like 2 S homeolog antibody, nuclear factor, erythroid 2 like 2 antibody, nuclear factor, erythroid derived 2, like 2 antibody, nuclear factor, erythroid 2-like 2 antibody, nfe2l2a antibody, nfe2l2.S antibody, NFE2L2 antibody, Nfe2l2 antibody
- Background
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NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other. NFE2L2 may be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM].
Alias Symbols: NRF2
Protein Interaction Partner: BACH1, HDAC3, WAC, FBXW11, KEAP1, TNNT1, MAPK7, HDAC2, HDAC1, MAFF, MAFG, MAFK, MAP2K2, MAP2K1, MAPK9, MAPK8, AKT1, UBC, NQO1, BRCA1, AHR, CREB3, NFE2L3, ENC1, SIAH2, NFE2, ATF4, Pparg, SUMO1, SUMO2, RNF4, BPTF, RBMX, KPNA3, SUMO3, MYC, DYT10, Ube2e1, PGA
Protein Size: 605 - Molecular Weight
- 68 kDa
- Gene ID
- 4780
- NCBI Accession
- NM_006164, NP_006155
- UniProt
- Q16236
- Pathways
- ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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