×
For best experience we recommend to activate Javascript in your browser.
MED6 antibody (N-Term)
MED6
Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MED6 Antibody
(hide)
Target
See all MED6 Antibodies
MED6
(Mediator Complex Subunit 6 (MED6))
Binding Specificity
All epitopes for MED6 antibodies
N-Term
Reactivity
All reactivities for MED6 antibodies
Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae
Host
All hosts for MED6 antibodies
Rabbit
Clonality
All clonalities for MED6 antibodies
Polyclonal
Conjugate
All conjugates for MED6 antibodies
This MED6 antibody is un-conjugated
Application
All applications for MED6 antibodies
Western Blotting (WB)
Sequence
ILNSGSVLDY FSERSNPFYD RTCNNEVVKM QRLTLEHLNQ MVGIEYILLH
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%
Characteristics
This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human MED6
Top Product
Discover our top product MED6 Primary Antibody
Alternatives
(show)
Application Details
(hide)
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeat freeze-thaw cycles.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MED6
(hide)
Target
MED6
(Mediator Complex Subunit 6 (MED6))
Alternative Name
MED6 (MED6 Products )
Synonyms
NY-REN-28 antibody, wu:fa14c11 antibody, zgc:86933 antibody, 1500012F11Rik antibody, AU019660 antibody, AV213303 antibody, RNA polymerase transcriptional regulation mediator-like protein antibody, mediator complex subunit 6 antibody, hypothetical protein antibody, MED6 antibody, Med6 antibody, med6 antibody, CAALFM_C306170CA antibody
Background
MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Alias Symbols: NY-REN-28 Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED Protein Size: 246
Molecular Weight
28 kDa
Gene ID
10001
NCBI Accession
NM_005466 , NP_005457
UniProt
O75586
Pathways
Stem Cell Maintenance , Regulation of Lipid Metabolism by PPARalpha
Recently viewed
(hide)