HCFC1 antibody (N-Term)

Catalog No. ABIN2780670

Product Details anti-HCFC1 Antibody

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HCFC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GTRLLVFGGM VEYGKYSNDL YELQASRWEW KRLKAKTPKN GPPPCPRLGH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against HCFC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HCFC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 428 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HCFC1

Target: HCFC1 (Host Cell Factor C1 (VP16-Accessory Protein) (HCFC1))

Alternative Name: HCFC1 (HCFC1 Products)

Synonyms: CFF antibody, HCF-1 antibody, HCF1 antibody, HFC1 antibody, MRX3 antibody, VCAF antibody, AW060991 antibody, HCF antibody, RGD1563804 antibody, fc61g09 antibody, hcfc1 antibody, im:7159458 antibody, wu:fc61g09 antibody, wu:fj40c12 antibody, HCFC1 antibody, host cell factor C1 antibody, host cell factor C1a antibody, host cell factor antibody, host cell factor C1 (VP16-accessory protein) antibody, HCFC1 antibody, Hcfc1 antibody, hcfc1a antibody, LOC5571204 antibody, CpipJ_CPIJ014908 antibody

Background: HCFC1 is a member of the host cell factor family with five Kelch repeats, a fibronectin-like motif, and six HCF repeats, each of which contains a highly specific cleavage signal. This nuclear coactivator is proteolytically cleaved at one of the six possible sites, resulting in the creation of an N-terminal chain and the corresponding C-terminal chain. The final form of this protein consists of noncovalently bound N- and C-terminal chains. The protein is involved in control of the cell cycle and transcriptional regulation during herpes simplex virus infection.
Alias Symbols: CFF, HCF1, HFC1, VCAF, HCF-1
Protein Interaction Partner: FBXW11, BAP1, NUDCD3, CREB3, UBC, RPA3, RPA2, RPA1, EED, EEF1D, CREBZF, LMNA, OGT, POU2F1, NOTCH1, UL48, RBBP5, PPP1CB, PPP1CA, DPY30, WDR5, MAP3K7, HCFC1, EGFR, CLP1, YEATS2, CDK2, CUL3, USF1, NR2C1, THAP11, SIRT7, ELAVL1, SUMO2, ASH2L, SNRPN, SNRPB, YY1
Protein Size: 428

Molecular Weight: 45 kDa

Gene ID: 3054

NCBI Accession: NM_005334