ZNF76 antibody (N-Term)

Catalog No. ABIN2780514

Product Details anti-ZNF76 Antibody

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF76 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LSDGTTAYVQ QAVKGEKLLE GQVIQLEDGT TAYIHQVTVQ KEALSFEDGQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ZNF76. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF76

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 570 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ZNF76

Target: ZNF76 (Zinc Finger Protein 76 (Expressed in Testis) (ZNF76))

Alternative Name: ZNF76 (ZNF76 Products)

Synonyms: 2810027J07 antibody, BC025615 antibody, Znf76 antibody, D6S229E antibody, ZNF523 antibody, Zfp523 antibody, zinc finger protein 523 antibody, zinc finger protein 76 antibody, Zfp523 antibody, ZNF76 antibody

Background: ZNF76 belongs to the krueppel C2H2-type zinc-finger protein family. ZNF76 is a general transcription repressor targeting TATA-binding protein (TBP), through a process regulated by sumoylation. ZNF76 interacts with TBP through both its N and C termini, and both regions are required for ZNF76 to exert its inhibitory function on p53-mediated transactivation. As a TBP-interacting transcriptional modulator, ZNF76 is also regulated by alternative splicing.
Alias Symbols: ZNF523, Zfp523, D6S229E
Protein Interaction Partner: SMAD1, UBC, TBP, HDAC1, EP300, CAND1, ELAVL1, Pias1,
Protein Size: 570

Molecular Weight: 62 kDa

Gene ID: 7629

NCBI Accession: NM_003427, NP_003418

UniProt: P36508