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JunB antibody (N-Term)

JUNB Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780413
  • Target See all JunB (JUNB) Antibodies
    JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
    Binding Specificity
    • 29
    • 15
    • 15
    • 12
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 131
    • 59
    • 55
    • 9
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig
    Host
    • 123
    • 7
    • 1
    Rabbit
    Clonality
    • 117
    • 14
    Polyclonal
    Conjugate
    • 65
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This JunB antibody is un-conjugated
    Application
    • 87
    • 41
    • 31
    • 27
    • 26
    • 26
    • 16
    • 16
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    YGRAPGGLSL HDYKLLKPSL AVNLADPYRS LKAPGARGPG PEGGGGGSYF
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 93%
    Characteristics
    This is a rabbit polyclonal antibody against JUNB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human JUNB
    Top Product
    Discover our top product JUNB Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 347 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Trøen, Nygaard, Jenssen, Ikonomou, Tierens, Matutes, Gruszka-Westwood, Catovsky, Myklebost, Lauritzsen, Hovig, Delabie: "Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma." in: The Journal of molecular diagnostics : JMD, Vol. 6, Issue 4, pp. 297-307, (2004) (PubMed).

  • Target
    JunB (JUNB) (Jun B Proto-Oncogene (JUNB))
    Alternative Name
    JUNB (JUNB Products)
    Synonyms
    AP-1 antibody, junb antibody, wu:cegs2778 antibody, wu:fa92h07 antibody, wu:fq24h03 antibody, zgc:64066 antibody, MGC81322 antibody, JUNB antibody, junbl antibody, wu:fa95h09 antibody, wu:fj44e11 antibody, wu:fj68b07 antibody, zgc:63933 antibody, JunB proto-oncogene, AP-1 transcription factor subunit antibody, JunB proto-oncogene, AP-1 transcription factor subunit a antibody, jun B proto-oncogene L homeolog antibody, jun B proto-oncogene antibody, jun B proto-oncogene S homeolog antibody, JunB proto-oncogene, AP-1 transcription factor subunit b antibody, JUNB antibody, Junb antibody, junba antibody, junb.L antibody, junb antibody, junb.S antibody, junbb antibody
    Background
    The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. JunB is involved in many types of human carcinoma including T-cell lymphomas, CML,primary cutaneous lymphomas. Aberrantly expressed c-Jun and JunB are a hallmark of Hodgkin lymphoma cells, stimulate proliferation and synergize with NF-kappa B. JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.JunB is an important regulator of erythroid Differentiation.
    Alias Symbols: AP-1
    Protein Interaction Partner: BATF, FOS, RFWD2, C19orf68, USP24, TCERG1, ZNF595, PKIA, MAP2, APLP2, FOSL1, DDIT3, ATF3, BATF2, BATF3, TCL1A, FOSL2, NPM1, NEU1, SMAD4, HOXA7, BDNF, ATF4, MAPK6, UBC, TDG, SET, SAT1, MAPK9, BRCA1, SUMO2, Cebpb, EP300, SMURF1, YY1, CREBBP, SMARCA4, JDP2,
    Protein Size: 347
    Molecular Weight
    36 kDa
    Gene ID
    3726
    NCBI Accession
    NM_002229, NP_002220
    UniProt
    P17275
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