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EGR4 antibody (C-Term)

EGR4 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2780389
  • Target See all EGR4 Antibodies
    EGR4 (Early Growth Response 4 (EGR4))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 16
    • 16
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 17
    • 1
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EGR4 antibody is un-conjugated
    Application
    • 10
    • 5
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RSDHLTSHVR THTGEKPFAC DVCGRRFARS DEKKRHSKVH LKQKARAEER
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%
    Characteristics
    This is a rabbit polyclonal antibody against EGR4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human EGR4
    Top Product
    Discover our top product EGR4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 486 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EGR4 (Early Growth Response 4 (EGR4))
    Alternative Name
    EGR4 (EGR4 Products)
    Synonyms
    EGR4 antibody, NGFI-C antibody, NGFIC antibody, PAT133 antibody, NGF1-C antibody, pAT133 antibody, Egr4l1 antibody, early growth response 4 antibody, EGR4 antibody, Egr4 antibody
    Background
    The nerve growth factor-induced clone C (NGFI-C/EGR4) gene is a zinc-finger transcription factor that is rapidly induced by nerve growth factor in rat pheochromocytoma PC12 cells and by seizure in brain. NGFI-C/EGR4 is closely related to the previously described early response genes, nerve growth factor-induced clone A (NGFI-A or EGR1), EGR2, and EGR3. These four early response (immediate early) proteins all contain very similar zinc-finger DNA binding domains and five highly homologous subdomains. EGR-4 functionally cooperate with NFAT proteins and induce expression of IL-2 and TNFalpha. Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression.
    Alias Symbols: NGFIC, NGFI-C, PAT133
    Protein Interaction Partner: NFATC2,
    Protein Size: 486
    Molecular Weight
    51 kDa
    Gene ID
    1961
    NCBI Accession
    NM_001965, NP_001956
    UniProt
    Q05215
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