DR1 antibody (N-Term)

Catalog No. ABIN2780386

Product Details anti-DR1 Antibody

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MASSSGNDDD LTIPRAAINK MIKETLPNVR VANDARELVV NCCTEFIHLI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DR1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DR1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 176 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-DR1 antibody (ABIN2780386)

Deng, Malecová, Oelgeschläger, Roberts: "TFIIB recognition elements control the TFIIA-NC2 axis in transcriptional regulation." in: Molecular and cellular biology, Vol. 29, Issue 6, pp. 1389-400, (2009) (PubMed).

Target Details for DR1

Target: DR1 (TATA-Binding Protein-Associated Phosphoprotein (DR1))

Alternative Name: DR1 (DR1 Products)

Synonyms: BG:DS00929.3 antibody, CG4185 antibody, Dmel\\CG4185 antibody, Dr1 antibody, NC2 beta antibody, Nc2b antibody, dDr1 antibody, dNC2 antibody, wu:fj15f04 antibody, zgc:152914 antibody, 1700121L09Rik antibody, Dr1l antibody, NC2 antibody, NC2beta antibody, NC2-BETA antibody, Negative Cofactor 2beta antibody, TATA-BINDING PROTEIN-ASSOCIATED PHOSPHOPROTEIN antibody, TATA-binding protein-associated phosphoprotein antibody, putative tata-binding protein-associated phosphoprotein antibody, down-regulator of transcription 1 antibody, down-regulator of transcription 1, TBP-binding (negative cofactor 2) antibody, NC2beta antibody, ECU11_0730 antibody, EDI_229030 antibody, PTRG_08168 antibody, Smp_160150 antibody, EBI_26279 antibody, EBI_23074 antibody, VDBG_02216 antibody, dr1 antibody, Dr1 antibody, DR1 antibody

Background: DR1 is a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. DR1 is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. DR1 contains a histone fold motif
Alias Symbols: NC2, NC2-BETA
Protein Interaction Partner: POLE3, TBP, UBC, BTF3L4, LRSAM1, GOPC, NPLOC4, IPO11, DBNL, ARIH1, TTLL12, ARPC1B, UBE3A, METTL1, HSF1, XPO1, YEATS2, DRAP1, CREB1, CCDC101, TADA2B, SUPT20H, MBIP, WDR5, TADA3, KAT2B, MAP3K7, TADA2A, KAT2A, DR1, ELAVL1, NFYC, NFIL3, TTF2, IRF1,
Protein Size: 176

Molecular Weight: 19 kDa

Gene ID: 1810

NCBI Accession: NM_001938, NP_001929

UniProt: Q01658