Elf4 antibody (N-Term)

Catalog No. ABIN2780359

Product Details anti-Elf4 Antibody

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Elf4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAITLQPSDL IFEFASNGMD DDIHQLEDPS VFPAVIVEQV PYPDLLHLYS

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against ELF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ELF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 663 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Alternative Name: ELF4 (Elf4 Products)

Synonyms: ELF4 antibody, RGD1560743 antibody, ELFR antibody, MEF antibody, AV314029 antibody, BC042423 antibody, ENSMUSG00000053512 antibody, Gm9907 antibody, Mef antibody, E74 like ETS transcription factor 4 antibody, E74-like factor 4 (ets domain transcription factor) antibody, ELF4 antibody, Elf4 antibody

Background: ELF4 contains 1 ETS DNA-binding domain and belongs to the ETS family. It is transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. It transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. It acts synergistically with RUNX1 to transactivate the IL3 promoter and also transactivates the PRF1 promoter in natural killer (NK) cells. ELF4 plays a role in the development and function of NK and NK T-cells and in innate immunity.
Alias Symbols: MEF, ELFR
Protein Interaction Partner: NPM1, SET, CASP4, UBC, PML, SKP2, KDM5B, FBXO4, FBXO7, UBB, RUNX1,
Protein Size: 663

Molecular Weight: 71 kDa

Gene ID: 2000

NCBI Accession: NM_001421, NP_001412

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity