PDX1 antibody (N-Term)

Catalog No. ABIN2780330

Product Details anti-PDX1 Antibody

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MNGEEQYYAA TQLYKDPCAF QRGPAPEFSA SPPACLYMGR QPPPPPPHPF

Predicted Reactivity: Cow: 100%, Dog: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PDX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 283 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Alternative Name: PDX1 (PDX1 Products)

Synonyms: GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody

Background: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of
Alias Symbols: IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1, GSF
Protein Interaction Partner: UBC, MAPK14, PCIF1, Dlg4, ATF3, PBX1, XRCC5, PRKDC, XRCC6, ALK, SPOP, MAFA, NEUROD1, PDX1, IAPP, TCF3, SLC2A2, CREB1,
Protein Size: 283

Molecular Weight: 31 kDa

Gene ID: 3651

NCBI Accession: NM_000209, NP_000200

UniProt: P52945

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location