SP110 antibody (Middle Region)
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- Target See all SP110 Antibodies
- SP110 (SP110 Nuclear Body Protein (SP110))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SP110 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- LKAYCHPQSS FFTGIPFNIR DYGEPFQEAM WLDLVKERLI TEMYTVAWFV
- Predicted Reactivity
- Horse: 75%, Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SP110. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SP110
- Top Product
- Discover our top product SP110 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 713 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SP110 (SP110 Nuclear Body Protein (SP110))
- Alternative Name
- SP110 (SP110 Products)
- Synonyms
- SP110 antibody, IFI41 antibody, IFI75 antibody, IPR1 antibody, VODI antibody, 5031415C07Rik antibody, 52kDa antibody, 5830484A20Rik antibody, ENSMUSG00000075603 antibody, Ifi75 antibody, Ipr1 antibody, SP110 nuclear body protein antibody, Sp110 nuclear body protein antibody, SP110 antibody, Sp110 antibody
- Background
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The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. SP110 is a member of the SP100/SP140 family of nuclear body proteins and is a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.
Alias Symbols: FLJ22835, IFI41, IFI75, VODI, IPR1
Protein Interaction Partner: UBC, CEBPA, OSGEP, TSC22D1, TTR, TK1, SMN1, CDKN1A, ANXA7, ZSCAN9, NAP1L2, RUNX3, NDUFV2,
Protein Size: 713 - Molecular Weight
- 81 kDa
- Gene ID
- 3431
- NCBI Accession
- NM_080424, NP_536349
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