ZNF141 antibody (N-Term)

Catalog No. ABIN2780227

Product Details anti-ZNF141 Antibody

Target: ZNF141 (Zinc Finger Protein 141 (ZNF141))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZNF141 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KILQCKASVK VVSKFSNSNK RKTRHTGEKH FKECGKSFQK FSHLTQHKVI

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against ZNF141. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF141

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 474 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ZNF141 antibody (ABIN2780227)

Tommerup, Aagaard, Lund, Boel, Baxendale, Bates, Lehrach, Vissing: "A zinc-finger gene ZNF141 mapping at 4p16.3/D4S90 is a candidate gene for the Wolf-Hirschhorn (4p-) syndrome." in: Human molecular genetics, Vol. 2, Issue 10, pp. 1571-5, (1994) (PubMed).

Target Details for ZNF141

Target: ZNF141 (Zinc Finger Protein 141 (ZNF141))

Alternative Name: ZNF141 (ZNF141 Products)

Background: Zinc finger encoding genes would be good candidates for being involved in the multiple developmental defects associated with chromosomal aneusomy--because of their role as transcriptional regulators, their abundance in the genome and their known association with specific developmental disorders. A zinc finger encoding cDNA (ZNF141) of the C2-H2/KRAB subfamily has been mapped to the 4p- (Wolf-Hirschhorn) syndrome (WHS) chromosome region. ZNF141 was expressed ubiquitously at low levels in the analysed tissue. The identification of a candidate gene for a chromosomal aneusomy syndrome belonging to a class of evolutionary conserved genes will provide options for studying its normal and abnormal expression during mammalian embryogenesis.
Alias Symbols: D4S90, pH Z-44
Protein Interaction Partner: UBC, SUMO1, SUMO3,
Protein Size: 474

Molecular Weight: 55 kDa

Gene ID: 7700

NCBI Accession: NM_003441, NP_003432

UniProt: Q15928