SCN3B antibody (N-Term)
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- Target See all SCN3B Antibodies
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
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Binding Specificity
- N-Term
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Reactivity
- Rat, Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SCN3B antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- RPEGGKDFLI YEYRNGHQEV ESPFQGRLQW NGSKDLQDVS ITVLNVTLND
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SCN3B. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SCN3B
- Top Product
- Discover our top product SCN3B Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 215 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Differential expression of sodium channel ? subunits in dorsal root ganglion sensory neurons." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15044-53, (2012) (PubMed).
: "A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 3, pp. 270-8, (2009) (PubMed).
: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).
: "
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Differential expression of sodium channel ? subunits in dorsal root ganglion sensory neurons." in: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 15044-53, (2012) (PubMed).
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- Target
- SCN3B (Sodium Channel, Voltage-Gated, Type III, beta Subunit (SCN3B))
- Alternative Name
- SCN3B (SCN3B Products)
- Synonyms
- 1110001K16Rik antibody, 4833414B02Rik antibody, Scnb3 antibody, HSA243396 antibody, SCNB3 antibody, sodium voltage-gated channel beta subunit 3 antibody, sodium channel, voltage-gated, type III, beta antibody, SCN3B antibody, Scn3b antibody
- Background
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SCN3B is one member of the sodium channel beta subunits of voltage-gated sodium channels, which are responsible for the generation and propagation of action potentials in neurons and muscle. SCN3B influences the inactivation kinetics of the sodium channel.
Alias Symbols: HSA243396, SCNB3
Protein Interaction Partner: NFASC,
Protein Size: 215 - Molecular Weight
- 24 kDa
- Gene ID
- 55800
- NCBI Accession
- NM_018400, NP_060870
- UniProt
- Q9NY72
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