MAFA antibody (C-Term)
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- Target See all MAFA Antibodies
- MAFA (Transcription Factor MafA (MAFA))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MAFA antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- KLEVGRLAKE RDLYKEKYEK LAGRGGPGGA GGAGFPREPS PAQAGPGAAK
- Predicted Reactivity
- Human: 86%, Mouse: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Mafa. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product MAFA Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 359 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MAFA (Transcription Factor MafA (MAFA))
- Alternative Name
- Mafa (MAFA Products)
- Synonyms
- RIPE3b1 antibody, hMafA antibody, RGD1562627 antibody, 2F1-Ag antibody, MAFA antibody, MAFA-L antibody, SMaf1 antibody, mafl antibody, L-MAF antibody, MAFL antibody, Maf antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antibody, MAF bZIP transcription factor A antibody, killer cell lectin-like receptor subfamily G, member 1 antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antibody, monocyte to macrophage differentiation-associated antibody, Mafa antibody, MAFA antibody, Klrg1 antibody, mafa antibody, mafaa antibody, Mmd antibody
- Background
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Mafa acts as a transcriptional factor. Mafa specifically binds the insulin enhancer element RIPE3b. Mafa cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Mafa regulates the insulin gene transcription. Mafa is involved either as an oncogene or as a tumor suppressor, depending on the cell context.
Alias Symbols: RIPE3b1
Protein Interaction Partner: Psme3,
Protein Size: 359 - Molecular Weight
- 37 kDa
- Gene ID
- 378435
- NCBI Accession
- NM_194350, NP_919331
- UniProt
- Q8CF90
- Pathways
- Hormone Transport
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