HELT antibody (C-Term)

Catalog No. ABIN2780137

Product Details anti-HELT Antibody

Target: HELT (Helt BHLH Transcription Factor (HELT))

Binding Specificity: C-Term

Reactivity: Mouse, Human, Rat, Cow, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HELT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LPEPDFSYQL HAASPEFPGH SPGEATMFPQ GATPGSFPWP PGAARSPALP

Predicted Reactivity: Cow: 85%, Guinea Pig: 77%, Horse: 85%, Human: 85%, Mouse: 100%, Rabbit: 77%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against Helt. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Helt

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 240 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HELT

Target: HELT (Helt BHLH Transcription Factor (HELT))

Alternative Name: Helt (HELT Products)

Synonyms: HCM1228 antibody, HESL antibody, Mgn antibody, bHLHb44 antibody, A830086M02 antibody, Hesl antibody, megane antibody, Helt-ps1 antibody, RGD1564073 antibody, zgc:109704 antibody, helt bHLH transcription factor antibody, HELT antibody, Helt antibody, helt antibody

Background: Helt is a transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGCG-3' and is required for the development of GABAergic neurons.
Alias Symbols: A830086M02, Hesl, Mgn, megane
Protein Interaction Partner: Helt, Hey2, Hes5,
Protein Size: 240

Molecular Weight: 27 kDa

Gene ID: 234219

NCBI Accession: NM_173789, NP_776150

UniProt: Q7TS99

Pathways: Feeding Behaviour