DMBX1 antibody (Middle Region)

Catalog No. ABIN2780096

Product Details anti-DMBX1 Antibody

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Guinea Pig, Mouse, Dog, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DMBX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: LSLSEQSASE SAPEDQLDRE EDSRAEEPKA EKSPGSESKV PGCKRGSPKA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DMBX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse DMBX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 376 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DMBX1

Target: DMBX1 (Diencephalon/mesencephalon Homeobox 1 (DMBX1))

Alternative Name: DMBX1 (DMBX1 Products)

Synonyms: MBX antibody, OTX3 antibody, PAXB antibody, DMBX1 antibody, Atx antibody, Cdmx antibody, Mbx antibody, Otx3 antibody, mbx2 antibody, zgc:112395 antibody, dmbx1 antibody, mbx antibody, otx3 antibody, pox1 antibody, zMbx1 antibody, diencephalon/mesencephalon homeobox 1 antibody, diencephalon/mesencephalon homeobox 1b antibody, diencephalon/mesencephalon homeobox 1a antibody, DMBX1 antibody, Dmbx1 antibody, dmbx1b antibody, dmbx1a antibody

Background: Transcription factors containing a homeodomain play an important role in the organogenesis of vertebrates. Otx3/Dmbx1 is a member of paired class homeodomain transcription factors. Otx3/Dmbx1 represses the Otx2-mediated transactivation in the developing brain by forming heterodimer with Otx2 on the P3C (TAATCCGATTA) sequence in vitro.
Alias Symbols: Atx, Mbx, Cdmx, Otx3
Protein Interaction Partner: Otx2,
Protein Size: 376

Molecular Weight: 41 kDa

Gene ID: 140477

NCBI Accession: NM_001025567, NP_001020738

UniProt: Q91ZK3

Pathways: Feeding Behaviour